Bravo’s new late-night talk show “Watch What Happens: Live” is going to be a cross between the network’s reunion shows and “Playboy After Dark,” said host Andy Cohen. “It’s at midnight so it’s going to be a little loose in structure,” Cohen told the Daily News. “We’ll be sipping cocktails.”

Premiering tonight, the weekly “Watch What Happens” will feature Cohen, who is also the senior vice president of production and programming at Bravo. The interactive series will feature a weekly take on pop culture showcasing guests from Bravo’s most popular shows and the world of entertainment, and discussions on topics ranging from fashion to the hottest celebrity news of the week. “We’ll be taking questions via Twitter and Facebook, and phone calls,” said Cohen. “We wanted to provide a bridge between what just aired on the network and the audience, so this is going to be a very interactive experience.”

“Every year, before a reunion, I inevitably get a phone call or e-mail from someone telling me they don’t want to talk about X or Y, but I just tell them they should be prepared to, because it’s happening.” While Cohen is still lining up future guests for the show, he expects visits from the “Real Housewives of Atlanta” ladies in the coming weeks before that show returns for its second season July 30, as well as all his favorites from TV, movies and fashion. “There are certain people who I love and am obsessed with that I’m working on booking,” said Cohen. “It’s going to be a great lineup. It’s going to be very unexpected.”

Cohen’s first guest is “Real Housewives of New Jersey” star Danielle Staub. Staub is a controversial member thanks to a shady past that included a high-profile arrest, involvement with drug cartels, and a name change. “Those Smoking-Gun.com documents [detailing Staub's arrest] came out after we wrapped the reunion show, so I’m interested in those,” said Cohen. “And at the reunion, Caroline famously accused Danielle of something that Danielle [denied] all knowledge of, so I’m wondering if her memory has been jogged in the past few weeks.”

Watch What Happens: Live is set to premiere on Thursday, July 16 at midnight ET/PT.